Table 1 |
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|
Laboratory studies |
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| Parameter |
Level |
Normal |
|
|
||
| TSH |
13.83 mIU/L |
0.30 – 3.94 |
| T3 |
1.89 pg/mL |
2.42 – 4.36 |
| ACTH |
1601 pg/mL |
5.0 – 47.0 |
| Hematocrit |
29.7% |
37 – 52 |
| Hemoglobin |
9.9 g/dL |
12 – 18) |
| Immunoglobulin G |
4040 mg/dL |
751 – 1560 |
| Kappa light chains |
48.7 mg/dL |
absent |
| Direct Coombs' |
positive |
negative |
| Beta-2 microglobulin |
4.2 mg/L |
1.0 – 1.9 |
| D-dimer |
2527 ng/ml |
<500 |
| Factor V Leiden mutation |
heterozygote |
absent |
| ANA |
> 1/1280 "speckled" |
absent |
| RNP/Sm |
positive |
negative |
| SS-A/Ro |
positive |
negative |
|
|
||
|
Test results within normal range: electrolytes (including calcium), glucose, kidney and liver function tests, white blood cell count with differential and platelets, free T4, IgM, IgA, indirect Coombs' test, erythrocyte sedimentation rate, C-reactive protein, troponin T; global coagulation parameters; urine analysis, urinary free lambda light chains; anti-extractable nuclear antigens antibodies (SS-B/La, Scl-70 and Jo-1), anti-dsDNA; anti-mitochondrial (AMA), anti-neutrophil cytoplasmic (ANCA) against myeloperoxidase (MPO) and proteinase-3 (PR3), anti-liver kidney microsomal, anti-parietal cell, anti-transglutaminase IgA and IgG, and anti-cardiolipin IgG and IgM antibodies; rheumatoid factor; angiotensin converting enzyme; complement levels C3 and C4; candida culture, serology on single determination for hepatitis viruses A, B and C, human immunodeficiency virus antigen/antibody, cytomegalovirus, herpes simplex virus-1 and -2, and varicella-zoster virus. Elevated ACTH reduced within days to normal values upon administration of increased doses of cortisone acetate resulting in cortisol levels of around 400 ng/mL (normal range: 65 – 250). Abbreviations: ANA, antinuclear antibodies; RNP/Sm, combined nuclear ribonucleoprotein Smith antigen. |
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|
Adami et al. International Archives of Medicine 2009 2:15 doi:10.1186/1755-7682-2-15 |
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