International Archives of Medicine


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Congenital heart block associated with Sjögren syndrome: case report

Karwan A Moutasim1*, Penelope J Shirlaw2, Michael P Escudier3 and Timothy WJ Poate4

Author Affiliations

1 Cancer Sciences Division, School of Medicine, University of Southampton, Southampton SO16 6YD, UK

2 Department of Oral Medicine, Guy's and St. Thomas' NHS Foundation Trust, London SE1 9RT, UK

3 King's College London Dental Institute at Guy's, King's and St. Thomas' Hospitals, London SE1 9RT, UK

4 King's College Hospital NHS Foundation Trust, Denmark Hill, London SE5 9RS, UK

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International Archives of Medicine 2009, 2:21 doi:10.1186/1755-7682-2-21

Published: 28 July 2009

Abstract

Background

Congenital heart block is a rare complication of pregnancy associated with Sjögren Syndrome that may result in the death of the foetus or infant, or the need for pacing in the newborn or at a later stage.

Case report

The case is presented of a 64-year-old patient with primary Sjögren Syndrome and a history of having given birth to two sons with congenital heart block, both of whom required pacing several years later.

Conclusion

The literature relating to this association is discussed including the suggested mechanism, long-term outcome of mothers of children with congenital heart block and preventive treatment strategies.