Case report
A 44 year-old lady with chronic renal disease and intractable ulcers: a case report
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* Corresponding author: Thejeswi Pujar thejeswip@gmail.com
1 Kern Medical Center, 1830 Flower Street, Bakersfield, California 93305, USA
2 David Geffen School of Medicine at UCLA, Los Angeles, California, USA
3 Critical Care and Pulmonary Services, Kern Medical Center, 1830 Flower Street, Bakersfield, California 93305, USA
International Archives of Medicine 2009, 2:22 doi:10.1186/1755-7682-2-22
Published: 31 July 2009Abstract
Calciphylaxis is a rare but potentially fatal condition occurring in patients with end stage renal disease on dialysis. Due to interplay of various factors, disturbances occur in the metabolism of calcium and phosphate leading to calcification within the vessel walls. The net result is tissue ischemia and necrosis. Clinically this presents as painful non-healing skin ulcers, which contribute to significant morbidity and mortality due to septic progression of the lesion. In this case report, we highlight the rapidly progressive nature of this disease, its etiopathogenesis and the role of early diagnosis in preventing life-threatening complications.