International Archives of Medicine


Open Access Highly Access Original research

Common mitochondrial polymorphisms as risk factor for endometrial cancer

Anna M Czarnecka1,2*, Aleksandra Klemba1, Andrzej Semczuk3, Katarzyna Plak1, Barbara Marzec4, Tomasz Krawczyk5, Barbara Kofler6, Pawel Golik1,7 and Ewa Bartnik1,7

Author Affiliations

1 Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Pawinskiego 5a, 02-106, Warsaw, Poland

2 School of Molecular Medicine, Medical University of Warsaw, Zwirki i Wigury 61, 02-091 Warsaw, Poland

3 II Clinic and Ward of Gynecology, Medical University of Lublin, Lublin, Poland

4 Department of Human Genetics, Lublin University School of Medicine, Lublin, Poland

5 Clinical Pathology Laboratory, Monument Institute of Polish Mothers Health Center, Lodz, Poland

6 Department of Pediatrics, University Hospital Salzburg, Paracelsus Medical University, Müllner Hauptstr 48, A-5020 Salzburg, Austria

7 Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland

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International Archives of Medicine 2009, 2:33 doi:10.1186/1755-7682-2-33

Published: 28 October 2009

Additional files

Additional file 1:

Table S1. Germ-line polymorphisms in the D-loop region of mtDNA of the endometrial adenocarcinoma patients.

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Additional file 2:

Table S2. Germ-line polymorphisms in the coding region of mtDNA of the endometrial adenocarcinoma patients.

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Additional file 3:

Table S3. Statistical analysis of haplogroup distribution in endometrial carcinoma vs. general Polish population.

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Additional file 4:

Table S4. Summary of mtDNA polymorphisms relevant to establish European haplogroups and its relation to clinical medicine.

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Additional file 5:

Table S5. Clinical and pathological features of EC patients enrolled in the study.

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Additional file 6:

Table S6. RLFP analysis data for haplogroup assignment; restriction enzymes and primers used in the study are indicated.

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Additional file 7:

Table S7. Sequences of primers used for D-loop sequencing (listed according to start position in mtDNA).

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Additional file 8:

Table S8. Sequences of the primers used for haplogroup analysis (listed according to start position in mtDNA).

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