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Open Access Case report

An unusual complication of polyarteritis nodosa with massive retroperitoneal hemorrhage: a case report

Prashanth Peddi1*, Jagadeesh K Kalavakunta2, Madhavi Annakula1 and John R Armstrong3

Author Affiliations

1 Department of Internal Medicine, Michigan State University, Lansing, MI, USA

2 Department of Internal Medicine, Michigan State University, Kalamazoo Center for Medical studies, Kalamazoo, MI, USA

3 Department of Critical Care Medicine, Sparrow Hospital, East Lansing, MI, USA

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International Archives of Medicine 2010, 3:31  doi:10.1186/1755-7682-3-31

Published: 11 November 2010


Background and Case report

Polyarteritis Nodosa (PAN) is a systemic necrotizing vasculitis that affects medium-sized and occasionally involves small arteries leading to the disruption of the internal and external elastic lamina and contribute to the development of aneurysms. Aneurysms develop at bifurcation of major blood vessels; they are prone to thrombosis, rupture and haemorrhage. Retroperitoneal haemorrhage around kidneys was previously reported in patients with PAN. We report a case of massive retroperitoneal bleeding from inferior pancreaticoduodenal artery aneurysm rupture in a 70-year-old female with PAN.


Prognosis of untreated PAN is very poor with 20% 5 year survival rate, therefore early recognition of the disease will prevent catastrophic complications and improves survival.